METHENOLONE ACETATE 25 mg LANDERLAN
Primobolan in Pills
Each tablet contains:
Methenolone Acetate ………………25mg
Excipients ……………………… q.s.p.
Content: 30 Tablets
MECHANISM OF ACTION
Anabolic androgens are steroids derived from testosterone that are intended to chemically decrease the androgenic and virilizing effects and increase the anabolic actions. According to their chemical structure and function they are divided into three groups. The second group is that of dihydrotestosterone (DHT) and derivatives, methenolone. Testosterone and androgens readily cross the cell membrane and bind to specific intracellular receptors, these receptors that have been purified are proteins with a molecular weight of approximately 120 kilodaltons. Its synthesis is genetically determined on the X chromosome. DHT binds to a receptor site near a terminal carboxyl group. The steroid receptor complex is activated and transported to the cell nucleus and binds to a DNA receptor site, increasing the activity of RNA polymerase and the formation of messenger RNAs, stimulating the synthesis of cellular proteins ultimately responsible for physiopharmacological actions.
By intramuscular route they are pharmacologically active, testosterone is introduced by simple diffusion in daily cells given its liposolubility, in many target tissues it is enzymatically converted to DHT by the action of an enzyme called t5-alpha-reductase, it is more active than testosterone . Biotransformation occurs in the liver, the main metabolites are eliminated in the urine. Maximum concentrations are reached 6-11 days after the administered injection.The absolute bioavailability of methenolone enanthate is 100%.
As for methenolone acetate, it is the oral form and is a derivative of DHT and has a similar mechanism to all anabolic androgenic steroids. It is metabolized in the liver and the elimination half-life is detected in the urine up to 5 days after a single administration and the duration is approximately 24 hours.
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