What is sibutramine?
The sibutramine (C17H26NCl) is an anorectic drug used to treat obesity.
It is a norepinephrine, serotonin, and dopamine reuptake inhibitor for the treatment of obesity and overweight, including weight loss and maintenance, when medically indicated, in conjunction with a low-calorie diet, such as obese patients with a of initial body mass ³ 30 kg/m2 or ³ 27 kg/m2 in the presence of other risk factors (example: arterial hypertension, diabetes, dyslipidemia).
The SIBUTRAMINE It should be used as part of a comprehensive weight management program that includes diet, exercise, and lifestyle changes.
What is sibutramine used for?
It is an appetite suppressant that works on the central nervous system, with specific areas in the brain.
It also stimulates thermogesis. Although very little.
It has function as an antidepressant. Controls anxiety and inhibits impulses
Sibutramine is indicated in conjunction with a low-calorie diet and a proper lifestyle, including exercise and healthy habits.
What effects does it have?
Sibutramine acts at the level of the central nervous system, inhibiting the reuptake of serotonin (5-HT) and norepinephrine. The potentiation of the effect of serotonin (HT2A/2C receptors) and norepinephrine (beta 1) at the central level would be responsible for the feeling of satiety, while the effect on peripheral noradrenergic receptors (beta 3) would cause an increase in caloric expenditure due to increased metabolic rate.
How to take Sibutramine and dosage?
Overweight patients and concomitant conditions, one 10 mg tablet for a period of 6 to 24 months.
Obese patients without concomitant conditions, one 20 mg tablet for a period of 6 to 24 months.
It is recommended that overweight patients with concomitant conditions who have not lost 2 kg or more during the first month of treatment and who have not experienced any adverse events, increase the dose to 20 mg.
Use in women:
The use in women can be used without problem in the same doses described above.
The manufacturer indicates that should not be used during pregnancy, a fertile woman should have a good contraceptive method while she is using Sibutramine.
In Lactation there is no evidence if it is excreted in milk, so it is recommended to avoid its use in this period.
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Sibutramine or Clenbuterol?
Sibutramine and Clenbuterol they work differently so they don't compete for the central nervous system. In fact they can work together to have better results.
Since the Clenbuterol performs Thermogenesis which is the elevation of body temperature and promotes the use of fatty tissue as energy.
And sibutramine suppresses appetite so together they work well.
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Where to Buy Sibutramine in Mexico at the Best Price?
In Mexico, the pharmaceutical product does not exist since it was removed from pharmacies in 2010. But there are laboratories that sell the product for its active substance as a generic version.
Even so, you can find a variety of quality between laboratories and other more false ones, so care must be taken where the product is purchased.
We for more than 10 years sell the best laboratories that can be obtained in this country, so you can Buy Sibutramine at the best price in Mexico in our store in a safe way.
How to know if it is original?
Serious labs have various hallmarks of originality such as badges and/or holograms. Normally on the laboratories website you can ask for reports and confirm if the product in question is original.
What side effects does it have?
Although it is chemically related to amphetamine, it is not a classic anorectic: its stimulant effects are significantly less, and discontinuation of treatment does not result in a withdrawal syndrome. But it can produce some side effects, such as:
- Increased blood pressure and heart rate
- dry mouth
History or presence of major alterations in eating.
Known hypersensitivity to SIBUTRAMINA or to any of the components of the product.
Concomitant use of monoamine oxidase inhibitors (MAOIs). An interval of at least two weeks should be allowed after discontinuation of MAOIs before starting SIBUTRAMINA therapy (see Drug and Other Interactions).
Concomitant use of other centrally acting weight loss agents.
It is not recommended in the following cases:
- arterial hypertension,
- history of heart disease,
- eating disorders (anorexia and bulimia),
- pregnancy and lactation.
Before using Sibutramine, it is recommended to carry out the corresponding studies. The responsibility lies with who consumes it.